Cargando…

1846. Quality of Life Impairment and Difficulty to Work Associated with Post-COVID Syndrome: A Cross-Sectional Study

BACKGROUND: Following SARS-CoV-2 virus infection, patients may suffer from long-lasting symptoms regardless of disease severity. Preliminary results show limitations in health-related quality of life (HRQoL). The aim of this study is to evaluate the change in the quality of life of COVID-19-infected...

Descripción completa

Detalles Bibliográficos
Autores principales: Kochuparambil, Jose J, Raju, Jomel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677222/
http://dx.doi.org/10.1093/ofid/ofad500.1674
_version_ 1785150079102877696
author Kochuparambil, Jose J
Raju, Jomel
author_facet Kochuparambil, Jose J
Raju, Jomel
author_sort Kochuparambil, Jose J
collection PubMed
description BACKGROUND: Following SARS-CoV-2 virus infection, patients may suffer from long-lasting symptoms regardless of disease severity. Preliminary results show limitations in health-related quality of life (HRQoL). The aim of this study is to evaluate the change in the quality of life of COVID-19-infected patients depending on the duration of the infection and the accumulation of symptoms. METHODS: The study population consisted of patients (18–65 years) presenting to the Post-COVID outpatient clinic of the tertiary care hospital in India, between March and October 2022. The HRQoL was assessed by the use of the RehabNeQ and the SF-36. Data analysis was descriptive with frequencies, means, and/or percentages. In addition, a univariate analysis of variance was performed to show the dependence of physical and psychological HRQoL on specific factors. This was finally tested for significance at an alpha level of 5%. RESULTS: Data from 318 patients were analyzed, most of whom had 3–6 months of infection (56%) and 5–10 symptoms persisted (60.4%). Both mental (MCS) and physical sum score (PCS) of HRQoL of the COVID-19 infected population were significantly lower than those of the normal population without a history of COVID-19 infection (p < .001). The number of remaining symptoms (MCS p = .0034, PCS p = .000) as well as the perceived ability to work (MCS p = .007, PCS p = .000), influenced the HRQoL. CONCLUSION: The HRQoL of patients with Post-COVID-syndrome is still reduced months after infection and so is their occupational performance. In particular, the number of symptoms could have an influence on this deficit, which would need to be further investigated. Further research is needed to detect other factors influencing HRQoL and to implement appropriate therapeutic interventions. DISCLOSURES: All Authors: No reported disclosures
format Online
Article
Text
id pubmed-10677222
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-106772222023-11-27 1846. Quality of Life Impairment and Difficulty to Work Associated with Post-COVID Syndrome: A Cross-Sectional Study Kochuparambil, Jose J Raju, Jomel Open Forum Infect Dis Abstract BACKGROUND: Following SARS-CoV-2 virus infection, patients may suffer from long-lasting symptoms regardless of disease severity. Preliminary results show limitations in health-related quality of life (HRQoL). The aim of this study is to evaluate the change in the quality of life of COVID-19-infected patients depending on the duration of the infection and the accumulation of symptoms. METHODS: The study population consisted of patients (18–65 years) presenting to the Post-COVID outpatient clinic of the tertiary care hospital in India, between March and October 2022. The HRQoL was assessed by the use of the RehabNeQ and the SF-36. Data analysis was descriptive with frequencies, means, and/or percentages. In addition, a univariate analysis of variance was performed to show the dependence of physical and psychological HRQoL on specific factors. This was finally tested for significance at an alpha level of 5%. RESULTS: Data from 318 patients were analyzed, most of whom had 3–6 months of infection (56%) and 5–10 symptoms persisted (60.4%). Both mental (MCS) and physical sum score (PCS) of HRQoL of the COVID-19 infected population were significantly lower than those of the normal population without a history of COVID-19 infection (p < .001). The number of remaining symptoms (MCS p = .0034, PCS p = .000) as well as the perceived ability to work (MCS p = .007, PCS p = .000), influenced the HRQoL. CONCLUSION: The HRQoL of patients with Post-COVID-syndrome is still reduced months after infection and so is their occupational performance. In particular, the number of symptoms could have an influence on this deficit, which would need to be further investigated. Further research is needed to detect other factors influencing HRQoL and to implement appropriate therapeutic interventions. DISCLOSURES: All Authors: No reported disclosures Oxford University Press 2023-11-27 /pmc/articles/PMC10677222/ http://dx.doi.org/10.1093/ofid/ofad500.1674 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Kochuparambil, Jose J
Raju, Jomel
1846. Quality of Life Impairment and Difficulty to Work Associated with Post-COVID Syndrome: A Cross-Sectional Study
title 1846. Quality of Life Impairment and Difficulty to Work Associated with Post-COVID Syndrome: A Cross-Sectional Study
title_full 1846. Quality of Life Impairment and Difficulty to Work Associated with Post-COVID Syndrome: A Cross-Sectional Study
title_fullStr 1846. Quality of Life Impairment and Difficulty to Work Associated with Post-COVID Syndrome: A Cross-Sectional Study
title_full_unstemmed 1846. Quality of Life Impairment and Difficulty to Work Associated with Post-COVID Syndrome: A Cross-Sectional Study
title_short 1846. Quality of Life Impairment and Difficulty to Work Associated with Post-COVID Syndrome: A Cross-Sectional Study
title_sort 1846. quality of life impairment and difficulty to work associated with post-covid syndrome: a cross-sectional study
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677222/
http://dx.doi.org/10.1093/ofid/ofad500.1674
work_keys_str_mv AT kochuparambiljosej 1846qualityoflifeimpairmentanddifficultytoworkassociatedwithpostcovidsyndromeacrosssectionalstudy
AT rajujomel 1846qualityoflifeimpairmentanddifficultytoworkassociatedwithpostcovidsyndromeacrosssectionalstudy