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682. Novel rpoB mutations and trends in clinical Clostridioides difficile isolates with reduced fidaxomicin susceptibility
BACKGROUND: Fidaxomicin use is increasing to treat Clostridioides difficile infection (CDI) following clinical treatment guideline updates placing it as first-line therapy. This puts a selection pressure on the development of fidaxomicin resistance, which has been associated with in vitro fitness co...
Autores principales: | Gonzales-Luna, Anne J, Le, Thanh, Eubank, Taryn A, Karim, Md Ekramul, Jahangir Alam, M, Begum, Khurshida, Garey, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677244/ http://dx.doi.org/10.1093/ofid/ofad500.744 |
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