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2566. Effect of CYP2C19 on Voriconazole Pharmacokinetics in Children with Malignancy or Inborn Errors in Immunity
BACKGROUND: Voriconazole pharmacokinetics (PK) are known to be affected by genetic polymorphisms of drug-metabolizing enzymes such as CYP2C19; however, such information is limited for the pediatric population. METHODS: This was a single-center population PK study. Information regarding patient backg...
Autores principales: | Shoji, Kensuke, Hikino, Keiko, Saito, Jumpei, Matsui, Toshihiro, Utano, Tomoyuki, Takebayashi, Akira, Tomizawa, Daisuke, Kato, Motohiro, Matsumoto, Kimikazu, Ishikawa, Takashi, Kawai, Toshinao, Nakamura, Hidefumi, Miyairi, Isao, Terao, Chikashi, Mushiroda, Taisei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677247/ http://dx.doi.org/10.1093/ofid/ofad500.2183 |
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