2554. What’s Weight Got to Do with It? Prospective Pharmacokinetic/Pharmacodynamic Evaluation of Fixed-Dose Daptomycin

BACKGROUND: As daptomycin (DAP) CL does not scale proportionally with weight, fixed-dose DAP has been proposed to optimize efficacy and mitigate toxicity. This study evaluated systemic exposure of a fixed dose (750 mg) of DAP in patients with Staphylococcus aureus infections. METHODS: Adult non-ICU...

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Detalles Bibliográficos
Autores principales: Olney, Katie B, Thomas, Jenni, Pai, Manjunath P, Burgess, Donna R, Olney, William, Bruning, Rebecca, Griffith, Kamron Amir, Casaus, Danielle, Crance, Elizabeth, Burgess, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677270/
http://dx.doi.org/10.1093/ofid/ofad500.2171

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