2552. Comparative Pharmacodynamic Evaluation of Commonly Utilized, Oral, 1(st) - 3(rd) Generation Cephalosporins against S. aureus and E. coli in the Mouse Thigh Infection Model

BACKGROUND: Cephalexin (LEX), cefuroxime axetil (CXM), and cefpodoxime (CPD) are common oral cephalosporins used to treat gram-positive and gram-negative infections. However, there is a paucity of PK/PD analyses to inform optimal dosing regimens, which drug may be preferred for a particular organism...

Descripción completa

Detalles Bibliográficos
Autores principales: Lepak, Alexander, Bhavnani, Sujata M, Vincent, Catharine, VanScoy, Brian D, Sader, Helio S, Andes, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677376/
http://dx.doi.org/10.1093/ofid/ofad500.2169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677376/
http://dx.doi.org/10.1093/ofid/ofad500.2169

Ejemplares similares