2555. Metronidazole Dosing in Patients with and without Obesity Undergoing Colorectal Surgery: Should body size or composition be a factor?

BACKGROUND: Metronidazole (MET) is administered on a fixed-dose basis irrespective of body size in adults but studies suggest that dose adjustment may be needed (PMID: 33969405). This study evaluated plasma and fat tissue pharmacokinetics (PK) of MET in patients undergoing elective colorectal surger...

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Autores principales: Pai, Manjunath P, Matvekas, Aleksas, Rajanayake, Krishani, Carrier, Theresa, Nguyen, Allison, Ross, Brian, Sullivan, June, Alikhani, Radin, Abdelnabi, Mohamed, Regenbogen, Scott, Byrn, John, Su, Grace, Wang, Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677456/
http://dx.doi.org/10.1093/ofid/ofad500.2172

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