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2160. Emergence of INDEL Mutations in KPC-2: Insights into Ceftazidime-Avibactam and Imipenem-Relebactam Efficacy

BACKGROUND: Enterobacterales producing KPC-2 and KPC-3 β-lactamases (Bla) are a significant clinical threat. Ceftazidime/avibactam (CZA) and imipenem/relebactam (IMI/REL) are successful in the treatment for these infections. Unfortunately, CZA-resistant isolates are emerging as a result of amino aci...

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Detalles Bibliográficos
Autores principales:	Brunetti, Florencia, Bethel, Christopher R, Sanz, María Belén, Pasterán, Fernando, Gutkind, Gabriel, Gomez, Sonia, Bonomo, Robert A, Power, Pablo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Abstract
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677562/ http://dx.doi.org/10.1093/ofid/ofad500.1783

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