489. Spatial transcriptomic analysis of placental tissue demonstrates differential gene expression in pregnancies with SARS-CoV-2 infection, SARS-CoV-2 placentitis, and controls

BACKGROUND: SARS-CoV-2 infection in pregnancy can cause placental abnormalities such as “SARS-CoV-2 placentitis” (histiocytic intervillositis, perivillous fibrin deposition, and villous trophoblast necrosis) that is irrespective of infection severity and associated with stillbirth. Mechanisms of SAR...

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Detalles Bibliográficos
Autores principales: Mithal, Leena B, Lorenzo-Redondo, Ramon, Sunderraj, Ashwin, Shanes, Elisheva D, Goldstein, Jeffrey A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677611/
http://dx.doi.org/10.1093/ofid/ofad500.558

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