276. A Focused Screen Identifies Essential Genes Enabling Increased Expansion in Hematopoietic Stem Cells to Generate Human Neutrophils

BACKGROUND: Cellular therapies are of growing clinical interest, particularly for patients with deficiencies in white blood cell number related to chemotherapy or radiation exposure. Neutrophils are the predominant peripheral white blood cell, and their versatility and efficacy in fighting infection...

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Detalles Bibliográficos
Autores principales: Jeffries, Nathan E, Timmer, Kyle, Yvanovich, Emma, Floyd, Daniel, Mansour, Michael, Sykes, David B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
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Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677620/
http://dx.doi.org/10.1093/ofid/ofad500.348

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