505. Drug-drug Interaction Profiling of Obeldesivir, A Promising Oral Treatment for COVID-19

BACKGROUND: Obeldesivir (ODV), an orally administered RNA-dependent RNA polymerase inhibitor, is a GS-441524 prodrug under investigation for the treatment of COVID-19. Herein, we assessed ODV as both perpetrator and victim of DDIs in healthy adults. METHODS: This Phase 1, open-label, multicenter, mu...

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Detalles Bibliográficos
Autores principales: Amini, Elham, Shelton, Mark, Raut, Anuja, Kwan, Anna, Xiao, Deqing, Chen, Shuguang, Madera, Sharline, Llewellyn, Joe, Winter, Helen, Humeniuk, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677664/
http://dx.doi.org/10.1093/ofid/ofad500.574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677664/
http://dx.doi.org/10.1093/ofid/ofad500.574

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