Jk(a) (Kidd-A) Variant in a Sickle Cell Disease Patient

Sickle cell disease (SCD) is a chronic and prevalent hemoglobin disorder with various manifestations and complications depending on the organs involved. Red cell transfusion either simple or exchange is crucial due to its prophylactic and therapeutic roles. We present a case showing serologic discre...

Descripción completa

Detalles Bibliográficos
Autores principales: Barouqa, Mohammad, Zhang, Xuebao, Walde, Ryan, Ahmed, Zan, Mohammed, Rasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677712/
https://www.ncbi.nlm.nih.gov/pubmed/38024097
http://dx.doi.org/10.7759/cureus.49451
_version_ 1785150195022954496
author Barouqa, Mohammad
Zhang, Xuebao
Walde, Ryan
Ahmed, Zan
Mohammed, Rasha
author_facet Barouqa, Mohammad
Zhang, Xuebao
Walde, Ryan
Ahmed, Zan
Mohammed, Rasha
author_sort Barouqa, Mohammad
collection PubMed
description Sickle cell disease (SCD) is a chronic and prevalent hemoglobin disorder with various manifestations and complications depending on the organs involved. Red cell transfusion either simple or exchange is crucial due to its prophylactic and therapeutic roles. We present a case showing serologic discrepancy between the red cells phenotype and the developed alloantibodies to emphasize the crucial role of molecular testing in SCD patients requiring chronic blood transfusion.
format Online
Article
Text
id pubmed-10677712
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-106777122023-11-26 Jk(a) (Kidd-A) Variant in a Sickle Cell Disease Patient Barouqa, Mohammad Zhang, Xuebao Walde, Ryan Ahmed, Zan Mohammed, Rasha Cureus Genetics Sickle cell disease (SCD) is a chronic and prevalent hemoglobin disorder with various manifestations and complications depending on the organs involved. Red cell transfusion either simple or exchange is crucial due to its prophylactic and therapeutic roles. We present a case showing serologic discrepancy between the red cells phenotype and the developed alloantibodies to emphasize the crucial role of molecular testing in SCD patients requiring chronic blood transfusion. Cureus 2023-11-26 /pmc/articles/PMC10677712/ /pubmed/38024097 http://dx.doi.org/10.7759/cureus.49451 Text en Copyright © 2023, Barouqa et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Genetics
Barouqa, Mohammad
Zhang, Xuebao
Walde, Ryan
Ahmed, Zan
Mohammed, Rasha
Jk(a) (Kidd-A) Variant in a Sickle Cell Disease Patient
title Jk(a) (Kidd-A) Variant in a Sickle Cell Disease Patient
title_full Jk(a) (Kidd-A) Variant in a Sickle Cell Disease Patient
title_fullStr Jk(a) (Kidd-A) Variant in a Sickle Cell Disease Patient
title_full_unstemmed Jk(a) (Kidd-A) Variant in a Sickle Cell Disease Patient
title_short Jk(a) (Kidd-A) Variant in a Sickle Cell Disease Patient
title_sort jk(a) (kidd-a) variant in a sickle cell disease patient
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677712/
https://www.ncbi.nlm.nih.gov/pubmed/38024097
http://dx.doi.org/10.7759/cureus.49451
work_keys_str_mv AT barouqamohammad jkakiddavariantinasicklecelldiseasepatient
AT zhangxuebao jkakiddavariantinasicklecelldiseasepatient
AT walderyan jkakiddavariantinasicklecelldiseasepatient
AT ahmedzan jkakiddavariantinasicklecelldiseasepatient
AT mohammedrasha jkakiddavariantinasicklecelldiseasepatient

Ejemplares similares