2346. Preliminary results of durable immune response induced by a self-amplifying mRNA (samRNA) SARS-CoV-2 vaccine candidate, GRT-R910, in adults previously vaccinated with mRNA or AZD1222 primary series

BACKGROUND: Neutralizing antibodies (nAbs) induced by authorized SARS-CoV-2 vaccines wane within months, requiring frequent boosters. Preliminary safety and immunogenicity of a samRNA-based SARS-CoV-2 vaccine candidate (GRT-R910) administered as a booster following AZD1222 primary series in older (≥...

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Detalles Bibliográficos
Autores principales: Uriel, Alison, Garbes, Pedro, Nagare, A, Kuan, J C, Palmer, Christine, Bae, K, Jooss, Karin, Rappaport, A, Kachura, Melissa, Kraemer, L, Venkatraman, Harshni, Jaroslavsky, Jason, Kounlavouth, Sonia, Marrali, M, Hart, Meghan, Betular, J, Allen, A, Green, C, Osanlou, O, Palfreeman, Adrian, Turgut, Tolga, Ustianowski, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10677884/
http://dx.doi.org/10.1093/ofid/ofad500.1968

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