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1334. Amino Acid Sequence Diversity of HIV-1 Viral Proteins Tat and Vpr in South African People Living with HIV: Implications for Neurocognitive Function

BACKGROUND: The transactivator of transcription (Tat) and Viral protein R (Vpr) of HIV-1 have functional roles in the neuropathophysiology of HIV-associated neurocognitive disorders (HAND). Pre-clinical studies have identified specific amino acid substitutions, including Tat T24K, C31S, R57S and Vpr...

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Detalles Bibliográficos
Autor principal:	Williams, Monray E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Abstract
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678049/ http://dx.doi.org/10.1093/ofid/ofad500.1171

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