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309. Optimized hematopoietic stem cell source for the ex vivo production of mature human neutrophils as a potential cell-based therapy for neutropenia
BACKGROUND: Neutrophils or granulocytes are the most common innate immune cell and are critical for eliminating invasive pathogens. Patients with low neutrophil counts face an increased risk of fatal opportunistic infections. Allogeneic granulocyte transfusions offer a solution to supplement endogen...
Autores principales: | Timmer, Kyle D, Floyd, Daniel, Jeffries, Nathan E, Yvanovich, Emma, Sykes, David B, Mansour, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678063/ http://dx.doi.org/10.1093/ofid/ofad500.381 |
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