Functional Connectivity Change Associated With Apolipoprotein E Allotypes Precedes Structural Connectivity and Neurodegeneration in Cognitive Normal Older Adults Without Cerebral Aβ Deposition

OBJECTIVE: Apolipoprotein E (APOE) gene is known to influence cerebral functional connectivity (FC) in Alzheimer’s disease continuum. We investigated association between APOE allotypes and FC, structural connectivity, and cortical thickness in amyloid-PET negative cognitive normal older adults (CN)....

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Detalles Bibliográficos
Autores principales: Wang, Sheng-Min, Kang, Dong Woo, Um, Yoo Hyun, Kim, Sunghwan, Lee, Chang Uk, Lim, Hyun Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neuropsychiatric Association 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678152/
https://www.ncbi.nlm.nih.gov/pubmed/37997333
http://dx.doi.org/10.30773/pi.2023.0164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678152/
https://www.ncbi.nlm.nih.gov/pubmed/37997333
http://dx.doi.org/10.30773/pi.2023.0164

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