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2746. Assessment of in vitro synergy between Piperacillin-Tazobactam-Meropenem and Imipenem-Meropenem against OXA-48 Producing Klebsiella pneumoniae Using Time-Kill Assays

BACKGROUND: Although double carbapenem regimens have reliable synergy against carbapenemase-producing Klebsiella pneumoniae (CP-Kp), the capacity of piperacillin-tazobactam (TZP) to provide synergistic activity with meropenem (MEM) is uncertain. METHODS: We used time-kill assays to evaluate synergy...

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Detalles Bibliográficos
Autores principales: Demir, Mervenur, Aslan, Abdullah Tarik, Seren Tanrıverdi, Elif, Otlu, Barış, Akova, Murat, Paterson, David, Harris, Patrick N A, Hazırolan, Gülşen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678274/
http://dx.doi.org/10.1093/ofid/ofad500.2357