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575. Optimization of a Nitrocefin-Based Rapid Test for the Detection of the Cefazolin Inoculum Effect (CzIE) in Methicillin-Susceptible Staphylococcus aureus
BACKGROUND: The cefazolin (Cz) inoculum effect, defined as a Cz MIC ≥16 µg/mL at 10(7) CFU/mL in MSSA isolates, has been associated with poor outcomes in adult patients with MSSA bacteremia and pediatric patients with osteomyelitis. Broth microdilution at high inoculum is the gold standard for the d...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678397/ http://dx.doi.org/10.1093/ofid/ofad500.644 |