575. Optimization of a Nitrocefin-Based Rapid Test for the Detection of the Cefazolin Inoculum Effect (CzIE) in Methicillin-Susceptible Staphylococcus aureus

BACKGROUND: The cefazolin (Cz) inoculum effect, defined as a Cz MIC ≥16 µg/mL at 10(7) CFU/mL in MSSA isolates, has been associated with poor outcomes in adult patients with MSSA bacteremia and pediatric patients with osteomyelitis. Broth microdilution at high inoculum is the gold standard for the d...

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Autores principales: Villegas, Sara I Gomez, Panesso, Diana, Singh, Kavindra, Rincon, Sandra, Carvajal, Lina Paola, Jacques-Palaz, Karen, Rizvi, Samie, Burnham, Carey-Ann, Abbott, April, Bard, Jennifer Dien, Westblade, Lars, Fritz, Stephanie A, Zimmer, Barbara, Dingle, Tanis C, Butler-Wu, Susan, Miller, William R, Reyes, Jinnethe, Arias, Cesar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678397/
http://dx.doi.org/10.1093/ofid/ofad500.644

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