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272. Dissecting Host-Commensal Interactions During Early Life to Identify Mechanisms of Protection Against Autoimmune Diabetes
BACKGROUND: Major Histocompatibility Complex (MHC) and Human Leukocyte Antigen (HLA) loci have strong genetic linkage with type 1 diabetes (T1D) in mice and humans, respectively. The diabetes-prone non-obese diabetic (NOD) strain of mice have a unique MHC-II locus with a distinct MHC-II A molecule (...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678457/ http://dx.doi.org/10.1093/ofid/ofad500.344 |