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2415. Health Outcome Disparities in Device-Associated Healthcare Infections Before and During the COVID-19 Pandemic
BACKGROUND: The COVID-19 pandemic has led to a considerable increase in Central-Line Associated Bloodstream Infections (CLABSI) and Catheter Associated Urinary Tract Infections (CAUTI). However, it remains unclear how this affected different population groups. METHODS: This retrospective observation...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678534/ http://dx.doi.org/10.1093/ofid/ofad500.2035 |
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author | Bischoff, Werner Evans, Joni Passaretti, Catherine Fernandez, Andrea |
author_facet | Bischoff, Werner Evans, Joni Passaretti, Catherine Fernandez, Andrea |
author_sort | Bischoff, Werner |
collection | PubMed |
description | BACKGROUND: The COVID-19 pandemic has led to a considerable increase in Central-Line Associated Bloodstream Infections (CLABSI) and Catheter Associated Urinary Tract Infections (CAUTI). However, it remains unclear how this affected different population groups. METHODS: This retrospective observational cohort study included CLABSI and CAUTI in a tertiary care facility. Information was collected on patient demographics, hospitalization, comorbidities, and COVID-19 status. Chi-square and Wilcoxon rank-sum tests were used for categorical and continuous variable comparisons. GEE models compared pre- and pandemic periods by interrupted time series analysis. RESULTS: From 1/1/2018 to 5/31/2022 98,791 patients had 151,550 hospital admissions. Of those, 17,796 patients had 29,483 central lines placed and 45,180 patients had 65,422 Foleys. 314 patients developed 338 CLABSI and 216 patients had 217 CAUTI. 1,552 patients tested positive for COVID-19 with 22 developing CLABSI and 14 CAUTI. The pre-pandemic downward trend in CLABSI and CAUTI was reversed during COVID-19 (p< 0.05). Black patients and those with other/unknown race had higher CLABSI per patient with central lines (p< 0.02) and higher device days (p< 0.0001) compared to white patients. Hispanic/Latino patients acquired more CLABSI per patient compared to non-Hispanic/non-Latino patients (p=0.04). During COVID-19 the already higher device days in Hispanic/Latino patients further increased compared to non-Hispanic/non-Latino patients (p< 0.0001). Black patients had higher CAUTI infection rates per patient with Foleys compared to white and other/unknown patients (p< 0.05). CAUTI per device days were also higher in black patients compared to white patients (p=0.02). No difference in CAUTI burden was detected for ethnic groups throughout the study period. Black and non-Hispanic/non-Latino patients had higher Foley usage days than other patients (p< 0.0001). Foley days decreased during COVID-19 (p=0.01). CONCLUSION: We detected health outcome disparities affecting black (CLABSI and CAUTI) and Hispanic/Latino (CLABSI) patients. Infections increased during the pandemic without altering race/ethnicity differences. Device utilization was significantly higher in affected groups. DISCLOSURES: All Authors: No reported disclosures |
format | Online Article Text |
id | pubmed-10678534 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-106785342023-11-27 2415. Health Outcome Disparities in Device-Associated Healthcare Infections Before and During the COVID-19 Pandemic Bischoff, Werner Evans, Joni Passaretti, Catherine Fernandez, Andrea Open Forum Infect Dis Abstract BACKGROUND: The COVID-19 pandemic has led to a considerable increase in Central-Line Associated Bloodstream Infections (CLABSI) and Catheter Associated Urinary Tract Infections (CAUTI). However, it remains unclear how this affected different population groups. METHODS: This retrospective observational cohort study included CLABSI and CAUTI in a tertiary care facility. Information was collected on patient demographics, hospitalization, comorbidities, and COVID-19 status. Chi-square and Wilcoxon rank-sum tests were used for categorical and continuous variable comparisons. GEE models compared pre- and pandemic periods by interrupted time series analysis. RESULTS: From 1/1/2018 to 5/31/2022 98,791 patients had 151,550 hospital admissions. Of those, 17,796 patients had 29,483 central lines placed and 45,180 patients had 65,422 Foleys. 314 patients developed 338 CLABSI and 216 patients had 217 CAUTI. 1,552 patients tested positive for COVID-19 with 22 developing CLABSI and 14 CAUTI. The pre-pandemic downward trend in CLABSI and CAUTI was reversed during COVID-19 (p< 0.05). Black patients and those with other/unknown race had higher CLABSI per patient with central lines (p< 0.02) and higher device days (p< 0.0001) compared to white patients. Hispanic/Latino patients acquired more CLABSI per patient compared to non-Hispanic/non-Latino patients (p=0.04). During COVID-19 the already higher device days in Hispanic/Latino patients further increased compared to non-Hispanic/non-Latino patients (p< 0.0001). Black patients had higher CAUTI infection rates per patient with Foleys compared to white and other/unknown patients (p< 0.05). CAUTI per device days were also higher in black patients compared to white patients (p=0.02). No difference in CAUTI burden was detected for ethnic groups throughout the study period. Black and non-Hispanic/non-Latino patients had higher Foley usage days than other patients (p< 0.0001). Foley days decreased during COVID-19 (p=0.01). CONCLUSION: We detected health outcome disparities affecting black (CLABSI and CAUTI) and Hispanic/Latino (CLABSI) patients. Infections increased during the pandemic without altering race/ethnicity differences. Device utilization was significantly higher in affected groups. DISCLOSURES: All Authors: No reported disclosures Oxford University Press 2023-11-27 /pmc/articles/PMC10678534/ http://dx.doi.org/10.1093/ofid/ofad500.2035 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstract Bischoff, Werner Evans, Joni Passaretti, Catherine Fernandez, Andrea 2415. Health Outcome Disparities in Device-Associated Healthcare Infections Before and During the COVID-19 Pandemic |
title | 2415. Health Outcome Disparities in Device-Associated Healthcare Infections Before and During the COVID-19 Pandemic |
title_full | 2415. Health Outcome Disparities in Device-Associated Healthcare Infections Before and During the COVID-19 Pandemic |
title_fullStr | 2415. Health Outcome Disparities in Device-Associated Healthcare Infections Before and During the COVID-19 Pandemic |
title_full_unstemmed | 2415. Health Outcome Disparities in Device-Associated Healthcare Infections Before and During the COVID-19 Pandemic |
title_short | 2415. Health Outcome Disparities in Device-Associated Healthcare Infections Before and During the COVID-19 Pandemic |
title_sort | 2415. health outcome disparities in device-associated healthcare infections before and during the covid-19 pandemic |
topic | Abstract |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678534/ http://dx.doi.org/10.1093/ofid/ofad500.2035 |
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