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2136. In Vitro Activity of Nacubactam (OP0595) Combined with Cefepime against Carbapenem-resistant Enterobacterales Isolated in Japan
BACKGROUND: Nacubactam is a new non-β-lactam diazabicyclooctane β-lactamase inhibitor that inhibits penicillin binding protein 2 (PBP2) of Enterobacterales and acts synergistically as a β-lactam enhancer when combined with β-lactams. Nacubactam is under development for the treatment of serious Gram-...
Autores principales: | Yanagihara, Katsunori, Mikamo, Hiroshige, Tateda, Kazuhiro, Doi, Yohei, Ohge, Hiroki, Takahashi, Satoshi, Kondo, Kenichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678573/ http://dx.doi.org/10.1093/ofid/ofad500.1759 |
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