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2136. In Vitro Activity of Nacubactam (OP0595) Combined with Cefepime against Carbapenem-resistant Enterobacterales Isolated in Japan

BACKGROUND: Nacubactam is a new non-β-lactam diazabicyclooctane β-lactamase inhibitor that inhibits penicillin binding protein 2 (PBP2) of Enterobacterales and acts synergistically as a β-lactam enhancer when combined with β-lactams. Nacubactam is under development for the treatment of serious Gram-...

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Detalles Bibliográficos
Autores principales:	Yanagihara, Katsunori, Mikamo, Hiroshige, Tateda, Kazuhiro, Doi, Yohei, Ohge, Hiroki, Takahashi, Satoshi, Kondo, Kenichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Abstract
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678573/ http://dx.doi.org/10.1093/ofid/ofad500.1759

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