1346. Genetic Variation at the Interferon λ Locus and Association with Clinical Outcome and Severity of COVID-19

BACKGROUND: People with obesity are at increased risk of severe COVID-19, with host inflammation a key contributor. Interferon (IFN) lambda 4 (IFNλ4) is a type III IFN expressed in individuals with the rs368234815-ΔG single nucleotide polymorphism (SNP) which is implicated in host immune responses t...

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Detalles Bibliográficos
Autores principales: Alalwan, Dana, Negi, Riya, García-León, Alejandro, Saini, Gurvin, Gaillard, Colette Marie, Kenny, Grace, Savinelli, Stefano, Feeney, Eoin R, Cotter, Aoife, Carr, Michael, Gonzalez, Gabriel, Landay, Alan, de Barra, Eoghan, Yousif, Obada, Horgan, Mary, Mallon, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678593/
http://dx.doi.org/10.1093/ofid/ofad500.1183

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