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2524. Safety and Pharmacokinetics of PA-001, a New Potential COVID-19 Drug That Targets the S2 Subunit of SARS-CoV-2 Spike Protein, in Healthy Subjects

BACKGROUND: Frequent emergence of new variants of the SARS-CoV-2 virus continues to be a concern in treatment of COVID-19 infection, despite the approval of several drugs in recent years. To address this problem, we identified a new macrocyclic peptide, PA-001, which targets the highly conserved S2...

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Detalles Bibliográficos
Autores principales: Kurasaki, Haruaki, Ohuchi, Masaki, Matsui, Katsuma, Matsumoto, Masatoshi, Nagatomo, Kazutaka, Kawamura, Naoki, Ito, Shoko, Yonemura, Takuma, Chiyoda, Takeshi, Yamamoto, Asuka, Shimoi, Akihito, Masuya, Keiichi, Kitamura, Hidetomo, Murakami, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678873/
http://dx.doi.org/10.1093/ofid/ofad500.2142

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