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2178. Resistance to Cefepime/Taniborbactam in NDM-1 -Are We Losing the Battle against MDROs?
BACKGROUND: Taniborbactam (TAN; Fig 1) is a novel cyclic boronate that inhibits Serine- and some Metallo-β-Lactamases like NDM and VIM. The combination cefepime (FEP)/ TAN has just completed a Phase III clinical trial. Notably, resistance mechanisms of FEP/TAN have already been described, such as th...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10678930/ http://dx.doi.org/10.1093/ofid/ofad500.1800 |