2551. Assessing Meropenem Concentrations in Children with Septic Shock: Population-Based Pharmacokinetic (PK) Modeling of Meropenem Demonstrates Variability from Acute Kidney (AKI) to Augmented Renal Clearance (ARC)

BACKGROUND: The primary objective of this study was to characterize meropenem (MERO) pharmacokinetics (PK) in critically ill infants and children with septic shock to develop dosing recommendations to achieve therapeutic drug exposure in this complex population with a spectrum of renal function from...

Descripción completa

Detalles Bibliográficos
Autores principales: Le, Jennifer, Huynh, Julie, Bradley, John S, Vo, Brandon, Momper, Jeremiah, Capparelli, Edmund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679014/
http://dx.doi.org/10.1093/ofid/ofad500.2168

Ejemplares similares

Ejemplares similares