Cargando…

Genetic evidence for causal effects of leukocyte counts on risk for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by the accumulation of leukocytes and inflammatory mediators within the synovial tissue. Leukocyte counts are proposed to play a role in the pathogenesis of RA. However, the causality remains unclear. To investigate the causal relation...

Descripción completa

Detalles Bibliográficos
Autores principales:	You, Jin-Mei, Zhang, Yao-Chen, Fan, Ke-Yi, Bai, Shang-Kai, Zhang, Zi-Yu, Zhang, He-Yi, Cheng, Ting, Huo, Yue-Hong, Wang, Cai-Hong, Li, Xiao-Feng, Zhang, Sheng-Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679084/ https://www.ncbi.nlm.nih.gov/pubmed/38008752 http://dx.doi.org/10.1038/s41598-023-46888-1

Ejemplares similares

Genetic association between interleukin-17 and susceptibility to rheumatoid arthritis
por: Zhao, Rong, et al.
Publicado: (2023)

Appraising causal risk and protective factors for rheumatoid arthritis: a systematic review and meta-analysis of Mendelian randomization
por: Gu, Peng, et al.
Publicado: (2023)

Expression of leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) on osteoclasts and its potential role in rheumatoid arthritis
por: Zhang, Yuan, et al.
Publicado: (2013)

Yoga, rheumatoid arthritis & human leukocyte antigen-G
por: Mittal, Balraj
Publicado: (2022)

Abnormalities of Peripheral Lymphocyte Subsets in Rheumatoid Arthritis Patients Complicated with Osteoporosis
por: Cheng, Ting, et al.
Publicado: (2022)

Identification of potential genetic causal variants for rheumatoid arthritis by whole-exome sequencing
por: Li, Ying, et al.
Publicado: (2017)

Mechanistic target of rapamycin (mTOR): a potential new therapeutic target for rheumatoid arthritis
por: Zhang, Fen, et al.
Publicado: (2023)

Serum metabolomic and lipidomic profiling identifies diagnostic biomarkers for seropositive and seronegative rheumatoid arthritis patients
por: Luan, Hemi, et al.
Publicado: (2021)

Causality of occupational exposure on rheumatoid arthritis and ankylosing spondylitis: a two-sample mendelian randomization study
por: Du, Kai, et al.
Publicado: (2023)

Quick Leukocyte Nucleus Segmentation in Leukocyte Counting
por: Wang, Yapin, et al.
Publicado: (2019)

PDCD5 as a Potential Biomarker for Improved Prediction of the Incidence and Remission for Patients with Rheumatoid Arthritis
por: Xiao, Juan, et al.
Publicado: (2023)

Rheumatoid arthritis and osteogenesis imperfecta: is there a genetic causal association?
por: Mormile, Ilaria, et al.
Publicado: (2022)

The Causal Relationship Between Rheumatoid Arthritis and Mechanical Complications of Prosthesis After Arthroplasty: A Two-Sample Mendelian Randomization Study
por: Cai, Yuanqing, et al.
Publicado: (2022)

Vitamin D Metabolic Pathway Genes Polymorphisms and Their Methylation Levels in Association With Rheumatoid Arthritis
por: Zhang, Tian-Ping, et al.
Publicado: (2021)

Causal association between rheumatoid arthritis and celiac disease: A bidirectional two-sample mendelian randomization study
por: Hua, Lijiangshan, et al.
Publicado: (2022)

Characteristics of the Gut Microbiome and Its Relationship With Peripheral CD4(+) T Cell Subpopulations and Cytokines in Rheumatoid Arthritis
por: Wang, Qi, et al.
Publicado: (2022)

Gastrointestinal safety of etoricoxib in osteoarthritis and rheumatoid arthritis: A meta-analysis
por: Feng, Xiaoting, et al.
Publicado: (2018)

The Contribution of Genetic Variation and Aberrant Methylation of Aryl Hydrocarbon Receptor Signaling Pathway Genes to Rheumatoid Arthritis
por: Zhang, Tian-Ping, et al.
Publicado: (2022)

Mendelian randomization study reveals a causal relationship between rheumatoid arthritis and risk for pre-eclampsia
por: Zhang, Dingyi, et al.
Publicado: (2022)

The Gut Microbiota and Its Relevance to Peripheral Lymphocyte Subpopulations and Cytokines in Patients with Rheumatoid Arthritis
por: Li, Yuan, et al.
Publicado: (2021)

Muscle mass loss is associated with physical dysfunction in patients with early rheumatoid arthritis
por: Pan, Jie, et al.
Publicado: (2022)

Smoothened Regulates Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via Activation of Rho GTPase Signaling
por: Peng, Wei-xiang, et al.
Publicado: (2017)

Higher Serum CCN3 Is Associated with Disease Activity and Inflammatory Markers in Rheumatoid Arthritis
por: Wei, Yingying, et al.
Publicado: (2020)

Association of KCNB1 to rheumatoid arthritis via interaction with HLA-DRB1
por: Xiao, Xiangjun, et al.
Publicado: (2009)

Decreased Expression of Sphingosine-1-Phosphate Receptor 1 in the Blood Leukocyte of Rheumatoid Arthritis Patients
por: Choi, Hyun Suk, et al.
Publicado: (2018)

Causal risk and protective factors in rheumatoid arthritis: A genetic update
por: Arleevskaya, M., et al.
Publicado: (2021)

Chinese registry of rheumatoid arthritis: IV. Correlation and consistency of rheumatoid arthritis disease activity indices in China
por: Song, Xing, et al.
Publicado: (2021)

Mid‐Term Outcomes of Arthroscopic Rotator Cuff Repair in Patients with Rheumatoid Arthritis
por: Zhang, Jie‐chao, et al.
Publicado: (2023)

Predictive value of drug efficacy by M6A modification patterns in rheumatoid arthritis patients
por: Song, Shan, et al.
Publicado: (2022)

Causal relationship between educational attainment and the risk of rheumatoid arthritis: a Mendelian randomization study
por: Huang, Guiwu, et al.
Publicado: (2021)

Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthritis
por: Raza, Karim, et al.
Publicado: (2006)

Low-dose IL-2 improved clinical symptoms by restoring reduced regulatory T cells in patients with refractory rheumatoid arthritis: A randomized controlled trial
por: Wang, Jia, et al.
Publicado: (2022)

Blood Leukocyte Counts in Alzheimer Disease
por: Luo, Jiao, et al.
Publicado: (2022)

Assessing the association of leukocyte telomere length with ankylosing spondylitis and rheumatoid arthritis: A bidirectional Mendelian randomization study
por: Wei, Donglei, et al.
Publicado: (2023)

Total knee arthroplasty for treatment of rheumatoid arthritis: A protocol for a systematic review of randomized controlled trial
por: Hou, Hai-bin, et al.
Publicado: (2019)

Isopsoralen ameliorates rheumatoid arthritis by targeting MIF
por: Han, Yi, et al.
Publicado: (2021)

Effect of solution-focused approach on anxiety and depression in patients with rheumatoid arthritis: A quasi-experimental study
por: Zhang, Chunli, et al.
Publicado: (2022)

Tender and swollen joint counts are poorly associated with disability in chikungunya arthritis compared to rheumatoid arthritis
por: Watson, Hugh, et al.
Publicado: (2021)

Leukocyte Count and Adverse Clinical Outcomes in Acute Ischemic Stroke Patients
por: Quan, Kehua, et al.
Publicado: (2019)

Causal graph-based analysis of genome-wide association data in rheumatoid arthritis
por: Alekseyenko, Alexander V, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_kdskcuntja8c653jq06dd8f0pb