2356. Close correlation of RBD with Live Viral Neutralising Capacity Across Variants and Time Supports Use of RBD Thresholds to Predict Protective Host Immunity

BACKGROUND: Although SARS-CoV-2 neutralising antibodies protect against severe COVID-19, whether circulating IgG titres reflect underlying host capacity to neutralise wild type (WT) and variants of concern (VOC) and what IgG threshold reflects sufficient neutralising capacity remains unclear. METHOD...

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Detalles Bibliográficos
Autores principales: Kenny, Grace, O’Reilly, Sophie R, Kelly, Neil Wrigley, Negi, Riya, Gaillard, Colette Marie, Alalwan, Dana, Saini, Gurvin, Alrawahneh, Tamara, Francois, Nathan, Angeliadis, Matthew, García-León, Alejandro, Tinago, Willard, Feeney, Eoin R, Cotter, Aoife, de Barra, Eoghan, Yousif, Obada, Horgan, Mary, Doran, Peter, Cox, Rebecca J, O’Shea, Donal, Olesen, Ole, Landay, Alan, Hogan, Andrew, Lelièvre, Jean-Daniel, Gautier, Virginie, Cornely, Oliver A, Mallon, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679122/
http://dx.doi.org/10.1093/ofid/ofad500.1977

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