1114. Exploring bactericidal activity and emergence of resistance for carbapenem-resistant Enterobacterales (CRE) with and without Klebsiella pneumoniae carbapenemase (KPC) treated with optimized meropenem (MEM) and meropenem-vaborbactam (MEV) exposures

BACKGROUND: KPC producing CRE are common in the US; however non-carbapenemase producing (CP) CRE are as common. KPC- and non-CP Escherichia coli (ECOL) and Enterobacter cloacae complex (ENTCC) demonstrate a range of MEM MICs. The objective of this study was to assess the in vitro killing activity of...

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Detalles Bibliográficos
Autores principales: Squires, Kevin M, Kline, Ellen G, Jones, Chelsea, Shields, Ryan K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679131/
http://dx.doi.org/10.1093/ofid/ofad500.087

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