ERRγ agonist under mechanical stretching manifests hypertrophic cardiomyopathy phenotypes of engineered cardiac tissue through maturation

Engineered cardiac tissue (ECT) using human induced pluripotent stem cell-derived cardiomyocytes is a promising tool for modeling heart disease. However, tissue immaturity makes robust disease modeling difficult. Here, we established a method for modeling hypertrophic cardiomyopathy (HCM) malignant...

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Detalles Bibliográficos
Autores principales: Fujiwara, Yuya, Miki, Kenji, Deguchi, Kohei, Naka, Yuki, Sasaki, Masako, Sakoda, Ayaka, Narita, Megumi, Imaichi, Sachiko, Sugo, Tsukasa, Funakoshi, Shunsuke, Nishimoto, Tomoyuki, Imahashi, Kenichi, Yoshida, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679535/
https://www.ncbi.nlm.nih.gov/pubmed/37802074
http://dx.doi.org/10.1016/j.stemcr.2023.09.003

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