Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications

Epigenome editing offers ethical advantages with non-inheritable gene expression control. However, concerns arise regarding potential transgenerational effects in humans. Ethical and regulatory evaluation is crucial, considering recent advancements and enhanced understanding of transgenerational epi...

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Detalles Bibliográficos
Autores principales: Sasaki-Honda, Mitsuru, Akatsuka, Kyoko, Sawai, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Forum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679648/
https://www.ncbi.nlm.nih.gov/pubmed/37922912
http://dx.doi.org/10.1016/j.stemcr.2023.10.003
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author Sasaki-Honda, Mitsuru
Akatsuka, Kyoko
Sawai, Tsutomu
author_facet Sasaki-Honda, Mitsuru
Akatsuka, Kyoko
Sawai, Tsutomu
author_sort Sasaki-Honda, Mitsuru
collection PubMed
description Epigenome editing offers ethical advantages with non-inheritable gene expression control. However, concerns arise regarding potential transgenerational effects in humans. Ethical and regulatory evaluation is crucial, considering recent advancements and enhanced understanding of transgenerational epigenetics in both mammals and humans.
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spelling pubmed-106796482023-11-02 Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications Sasaki-Honda, Mitsuru Akatsuka, Kyoko Sawai, Tsutomu Stem Cell Reports Forum Epigenome editing offers ethical advantages with non-inheritable gene expression control. However, concerns arise regarding potential transgenerational effects in humans. Ethical and regulatory evaluation is crucial, considering recent advancements and enhanced understanding of transgenerational epigenetics in both mammals and humans. Elsevier 2023-11-02 /pmc/articles/PMC10679648/ /pubmed/37922912 http://dx.doi.org/10.1016/j.stemcr.2023.10.003 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Forum
Sasaki-Honda, Mitsuru
Akatsuka, Kyoko
Sawai, Tsutomu
Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications
title Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications
title_full Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications
title_fullStr Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications
title_full_unstemmed Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications
title_short Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications
title_sort is epigenome editing non-inheritable? implications for ethics and the regulation of human applications
topic Forum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679648/
https://www.ncbi.nlm.nih.gov/pubmed/37922912
http://dx.doi.org/10.1016/j.stemcr.2023.10.003
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