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Single-cell RNA sequencing of human epidermis identifies Lunatic fringe as a novel regulator of the stem cell compartment

Single-cell RNA sequencing (scRNA-seq) of human skin provides a tool for validating observations from in vitro experimental models. By analyzing a published dataset of healthy adult epidermis, we confirm that the basal epidermal layer is heterogeneous, and three subpopulations of non-dividing cells...

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Detalles Bibliográficos
Autores principales: Negri, Victor Augusti, Louis, Blaise, Zijl, Sebastiaan, Ganier, Clarisse, Philippeos, Christina, Ali, Shahnawaz, Reynolds, Gary, Haniffa, Muzlifah, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679657/
https://www.ncbi.nlm.nih.gov/pubmed/37832539
http://dx.doi.org/10.1016/j.stemcr.2023.09.007