Cargando…

Contrast-enhanced spectral mammography: are kinetic patterns useful for differential diagnoses of enhanced lesions?

PURPOSE: To investigate the diagnostic efficiency of the kinetic curves of enhanced lesions on contrast-en-hanced spectral mammography (CESM) and whether they were similar to those of magnetic resonance imaging (MRI). METHODS: Two hundred and twelve patients with 222 enhanced lesions were included i...

Descripción completa

Detalles Bibliográficos
Autores principales: Rong, Xiaocui, Kang, Yihe, Xue, Jing, Han, Pengyin, Guang, Yang, Li, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679705/
https://www.ncbi.nlm.nih.gov/pubmed/36987842
http://dx.doi.org/10.5152/dir.2022.21562
_version_ 1785150627486105600
author Rong, Xiaocui
Kang, Yihe
Xue, Jing
Han, Pengyin
Guang, Yang
Li, Zhigang
author_facet Rong, Xiaocui
Kang, Yihe
Xue, Jing
Han, Pengyin
Guang, Yang
Li, Zhigang
author_sort Rong, Xiaocui
collection PubMed
description PURPOSE: To investigate the diagnostic efficiency of the kinetic curves of enhanced lesions on contrast-en-hanced spectral mammography (CESM) and whether they were similar to those of magnetic resonance imaging (MRI). METHODS: Two hundred and twelve patients with 222 enhanced lesions were included in this prospective study. Single-view craniocaudal of an affected breast was acquired at 3, 5, and 7 min after contrast media injection. The kinetic patterns of each lesion were evaluated and classified as elevated (type I), steady (type II), and depressed (type III). Statistical comparison used the chi-squared test, the receiver operating characteristic (ROC) curve, and Cohen’s kappa. RESULTS: Of 222 enhanced lesions, 140 were breast cancers, and 82 were benign lesions. The distribution of the kinetic curves for breast cancer was type I, 3.57%, type II, 35.71%, and type III, 60.72%. As for benign lesions, the distribution was type I, 43.90%, type II, 45.12%, and type III, 10.98%. The difference in the enhancement patterns between benign lesions and breast cancers was significant (P < 0.001). The likelihood of breast cancer related to a type I, II, and III curve was 12.20%, 57.47%, and 90.43%, respectively. For the enhancement intensity, the area under curve (AUC) of the ROC curves was 0.702 ± 0.036; for enhancement patterns, the AUC increased to 0.819 ± 0.030. Cohen’s kappa coefficient was 0.752 (P < 0.001) regarding the kinetic curves for CESM and MRI. CONCLUSION: The kinetic patterns on CESM show promise in differentiating between benign lesions and breast cancers, with good agreement, when compared with MRI.
format Online
Article
Text
id pubmed-10679705
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Galenos Publishing
record_format MEDLINE/PubMed
spelling pubmed-106797052023-12-05 Contrast-enhanced spectral mammography: are kinetic patterns useful for differential diagnoses of enhanced lesions? Rong, Xiaocui Kang, Yihe Xue, Jing Han, Pengyin Guang, Yang Li, Zhigang Diagn Interv Radiol Breast Imaging - Original Article PURPOSE: To investigate the diagnostic efficiency of the kinetic curves of enhanced lesions on contrast-en-hanced spectral mammography (CESM) and whether they were similar to those of magnetic resonance imaging (MRI). METHODS: Two hundred and twelve patients with 222 enhanced lesions were included in this prospective study. Single-view craniocaudal of an affected breast was acquired at 3, 5, and 7 min after contrast media injection. The kinetic patterns of each lesion were evaluated and classified as elevated (type I), steady (type II), and depressed (type III). Statistical comparison used the chi-squared test, the receiver operating characteristic (ROC) curve, and Cohen’s kappa. RESULTS: Of 222 enhanced lesions, 140 were breast cancers, and 82 were benign lesions. The distribution of the kinetic curves for breast cancer was type I, 3.57%, type II, 35.71%, and type III, 60.72%. As for benign lesions, the distribution was type I, 43.90%, type II, 45.12%, and type III, 10.98%. The difference in the enhancement patterns between benign lesions and breast cancers was significant (P < 0.001). The likelihood of breast cancer related to a type I, II, and III curve was 12.20%, 57.47%, and 90.43%, respectively. For the enhancement intensity, the area under curve (AUC) of the ROC curves was 0.702 ± 0.036; for enhancement patterns, the AUC increased to 0.819 ± 0.030. Cohen’s kappa coefficient was 0.752 (P < 0.001) regarding the kinetic curves for CESM and MRI. CONCLUSION: The kinetic patterns on CESM show promise in differentiating between benign lesions and breast cancers, with good agreement, when compared with MRI. Galenos Publishing 2023-03-29 /pmc/articles/PMC10679705/ /pubmed/36987842 http://dx.doi.org/10.5152/dir.2022.21562 Text en © Copyright 2023 by Turkish Society of Radiology | Diagnostic and Interventional Radiology, published by Galenos Publishing House. https://creativecommons.org/licenses/by-nc/4.0/Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Breast Imaging - Original Article
Rong, Xiaocui
Kang, Yihe
Xue, Jing
Han, Pengyin
Guang, Yang
Li, Zhigang
Contrast-enhanced spectral mammography: are kinetic patterns useful for differential diagnoses of enhanced lesions?
title Contrast-enhanced spectral mammography: are kinetic patterns useful for differential diagnoses of enhanced lesions?
title_full Contrast-enhanced spectral mammography: are kinetic patterns useful for differential diagnoses of enhanced lesions?
title_fullStr Contrast-enhanced spectral mammography: are kinetic patterns useful for differential diagnoses of enhanced lesions?
title_full_unstemmed Contrast-enhanced spectral mammography: are kinetic patterns useful for differential diagnoses of enhanced lesions?
title_short Contrast-enhanced spectral mammography: are kinetic patterns useful for differential diagnoses of enhanced lesions?
title_sort contrast-enhanced spectral mammography: are kinetic patterns useful for differential diagnoses of enhanced lesions?
topic Breast Imaging - Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679705/
https://www.ncbi.nlm.nih.gov/pubmed/36987842
http://dx.doi.org/10.5152/dir.2022.21562
work_keys_str_mv AT rongxiaocui contrastenhancedspectralmammographyarekineticpatternsusefulfordifferentialdiagnosesofenhancedlesions
AT kangyihe contrastenhancedspectralmammographyarekineticpatternsusefulfordifferentialdiagnosesofenhancedlesions
AT xuejing contrastenhancedspectralmammographyarekineticpatternsusefulfordifferentialdiagnosesofenhancedlesions
AT hanpengyin contrastenhancedspectralmammographyarekineticpatternsusefulfordifferentialdiagnosesofenhancedlesions
AT guangyang contrastenhancedspectralmammographyarekineticpatternsusefulfordifferentialdiagnosesofenhancedlesions
AT lizhigang contrastenhancedspectralmammographyarekineticpatternsusefulfordifferentialdiagnosesofenhancedlesions