Prolonged administration of total glucosides of paeony improves intestinal immune imbalance and epithelial barrier damage in collagen-induced arthritis rats based on metabolomics-network pharmacology integrated analysis

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovial inflammation and joint damage with complex pathological mechanisms. In recent years, many studies have shown that the dysregulation of intestinal mucosal immunity and the damage of the epithelial barrier are...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Rui, Peng, Jine, Ma, Zhe, Xie, Kaili, Li, Meijing, Wang, Qi, Guo, Xiaomeng, Nan, Nan, Wang, Sihui, Li, Jing, Xu, Jingjing, Gong, Muxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679728/
https://www.ncbi.nlm.nih.gov/pubmed/38026929
http://dx.doi.org/10.3389/fphar.2023.1187797

Ejemplares similares

Ejemplares similares