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Reactive oxygen species accelerate de novo acquisition of antibiotic resistance in E. coli

Reactive oxygen species (ROS) produced as a secondary effect of bactericidal antibiotics are hypothesized to play a role in killing bacteria. If correct, ROS may play a role in development of de novo resistance. Here we report that single-gene knockout strains with reduced ROS scavenging exhibited e...

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Detalles Bibliográficos
Autores principales: Qi, Wenxi, Jonker, Martijs J., de Leeuw, Wim, Brul, Stanley, ter Kuile, Benno H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679899/
https://www.ncbi.nlm.nih.gov/pubmed/38025768
http://dx.doi.org/10.1016/j.isci.2023.108373