Adrenocortical carcinoma – 12-year observation period in a single centre. Case report with literature review

BACKGROUND: Adrenocortical carcinoma (ACC) accounts for 0.2% of childhood malignancies. The most common symptom in children is rapidly progressive androgenization. Herein, we report a case of a patient with symptoms of hypercortisolaemia and androgenization, who was diagnosed with ACC. CASE PRESENTA...

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Detalles Bibliográficos
Autores principales: Dasiewicz, Patrycja, Moszczyńska, Elżbieta, Perek, Danuta, Polnik, Dariusz, Stepaniuk, Maria, Trubicka, Joanna, Grajkowska, Wiesława
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2023
Materias:
Case report | Opis przypadku
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679906/
https://www.ncbi.nlm.nih.gov/pubmed/38031835
http://dx.doi.org/10.5114/pedm.2023.132131
Descripción
Sumario:BACKGROUND: Adrenocortical carcinoma (ACC) accounts for 0.2% of childhood malignancies. The most common symptom in children is rapidly progressive androgenization. Herein, we report a case of a patient with symptoms of hypercortisolaemia and androgenization, who was diagnosed with ACC. CASE PRESENTATION: In a 10-year-old patient with ACC the course of the disease was complicated by 3 recurrences. She was treated with surgery, chemo-, and radiotherapy. Currently, 8 years after the end of treatment, there have been no signs of recurrence. CONCLUSIONS: A patient after ACC treatment requires regular check-ups and long-term observation. Constant supervision enables early diagnosis of disease recurrence, and the use of treatment improves the prognosis.

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