Adrenocortical carcinoma – 12-year observation period in a single centre. Case report with literature review

BACKGROUND: Adrenocortical carcinoma (ACC) accounts for 0.2% of childhood malignancies. The most common symptom in children is rapidly progressive androgenization. Herein, we report a case of a patient with symptoms of hypercortisolaemia and androgenization, who was diagnosed with ACC. CASE PRESENTA...

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Autores principales: Dasiewicz, Patrycja, Moszczyńska, Elżbieta, Perek, Danuta, Polnik, Dariusz, Stepaniuk, Maria, Trubicka, Joanna, Grajkowska, Wiesława
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2023
Materias:
Case report | Opis przypadku
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679906/
https://www.ncbi.nlm.nih.gov/pubmed/38031835
http://dx.doi.org/10.5114/pedm.2023.132131
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author Dasiewicz, Patrycja
Moszczyńska, Elżbieta
Perek, Danuta
Polnik, Dariusz
Stepaniuk, Maria
Trubicka, Joanna
Grajkowska, Wiesława
author_facet Dasiewicz, Patrycja
Moszczyńska, Elżbieta
Perek, Danuta
Polnik, Dariusz
Stepaniuk, Maria
Trubicka, Joanna
Grajkowska, Wiesława
author_sort Dasiewicz, Patrycja
collection PubMed
description BACKGROUND: Adrenocortical carcinoma (ACC) accounts for 0.2% of childhood malignancies. The most common symptom in children is rapidly progressive androgenization. Herein, we report a case of a patient with symptoms of hypercortisolaemia and androgenization, who was diagnosed with ACC. CASE PRESENTATION: In a 10-year-old patient with ACC the course of the disease was complicated by 3 recurrences. She was treated with surgery, chemo-, and radiotherapy. Currently, 8 years after the end of treatment, there have been no signs of recurrence. CONCLUSIONS: A patient after ACC treatment requires regular check-ups and long-term observation. Constant supervision enables early diagnosis of disease recurrence, and the use of treatment improves the prognosis.
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spelling pubmed-106799062023-09-01 Adrenocortical carcinoma – 12-year observation period in a single centre. Case report with literature review Dasiewicz, Patrycja Moszczyńska, Elżbieta Perek, Danuta Polnik, Dariusz Stepaniuk, Maria Trubicka, Joanna Grajkowska, Wiesława Pediatr Endocrinol Diabetes Metab Case report | Opis przypadku BACKGROUND: Adrenocortical carcinoma (ACC) accounts for 0.2% of childhood malignancies. The most common symptom in children is rapidly progressive androgenization. Herein, we report a case of a patient with symptoms of hypercortisolaemia and androgenization, who was diagnosed with ACC. CASE PRESENTATION: In a 10-year-old patient with ACC the course of the disease was complicated by 3 recurrences. She was treated with surgery, chemo-, and radiotherapy. Currently, 8 years after the end of treatment, there have been no signs of recurrence. CONCLUSIONS: A patient after ACC treatment requires regular check-ups and long-term observation. Constant supervision enables early diagnosis of disease recurrence, and the use of treatment improves the prognosis. Termedia Publishing House 2023-10-23 2023-09 /pmc/articles/PMC10679906/ /pubmed/38031835 http://dx.doi.org/10.5114/pedm.2023.132131 Text en © Copyright by PTEiDD 2023 https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), allowing third parties to download and share its works but not commercially purposes or to create derivative works.
spellingShingle Case report | Opis przypadku
Dasiewicz, Patrycja
Moszczyńska, Elżbieta
Perek, Danuta
Polnik, Dariusz
Stepaniuk, Maria
Trubicka, Joanna
Grajkowska, Wiesława
Adrenocortical carcinoma – 12-year observation period in a single centre. Case report with literature review
title Adrenocortical carcinoma – 12-year observation period in a single centre. Case report with literature review
title_full Adrenocortical carcinoma – 12-year observation period in a single centre. Case report with literature review
title_fullStr Adrenocortical carcinoma – 12-year observation period in a single centre. Case report with literature review
title_full_unstemmed Adrenocortical carcinoma – 12-year observation period in a single centre. Case report with literature review
title_short Adrenocortical carcinoma – 12-year observation period in a single centre. Case report with literature review
title_sort adrenocortical carcinoma – 12-year observation period in a single centre. case report with literature review
topic Case report | Opis przypadku
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679906/
https://www.ncbi.nlm.nih.gov/pubmed/38031835
http://dx.doi.org/10.5114/pedm.2023.132131
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