A green method to extract rutin from Sophora japonica L.

Sophora japonica L. contains high levels of rutin, which has great potential for use in pharmaceutical products for the treatment of diseases related to the cardiovascular and circulatory systems. We proposed a method of extracting rutin from S. japonica • Green deep eutectic solvents (DESs) of chol...

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Autores principales: Le, Nhan Trong, Nguyen, Trieu Phat Dac, Ho, Duc Viet, Phung, Huong Thanh, Nguyen, Hoai Thi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Chemical Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679937/
https://www.ncbi.nlm.nih.gov/pubmed/38023307
http://dx.doi.org/10.1016/j.mex.2023.102479
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author Le, Nhan Trong
Nguyen, Trieu Phat Dac
Ho, Duc Viet
Phung, Huong Thanh
Nguyen, Hoai Thi
author_facet Le, Nhan Trong
Nguyen, Trieu Phat Dac
Ho, Duc Viet
Phung, Huong Thanh
Nguyen, Hoai Thi
author_sort Le, Nhan Trong
collection PubMed
description Sophora japonica L. contains high levels of rutin, which has great potential for use in pharmaceutical products for the treatment of diseases related to the cardiovascular and circulatory systems. We proposed a method of extracting rutin from S. japonica • Green deep eutectic solvents (DESs) of choline chloride and ethylene glycol (ChCl-Eth) showed the highest extraction efficiency of rutin from S. japonica. • Under optimal conditions, the extraction yield of ChCl-Eth was 1.34 times higher than that of methanol as solvent. • Rutin was recovered from the DES extracts using water as the antisolvent with a high recovery yield, and the DESs of ChCl-Eth could be productively recovered and reused at least 3 times.
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spelling pubmed-106799372023-11-08 A green method to extract rutin from Sophora japonica L. Le, Nhan Trong Nguyen, Trieu Phat Dac Ho, Duc Viet Phung, Huong Thanh Nguyen, Hoai Thi MethodsX Chemical Engineering Sophora japonica L. contains high levels of rutin, which has great potential for use in pharmaceutical products for the treatment of diseases related to the cardiovascular and circulatory systems. We proposed a method of extracting rutin from S. japonica • Green deep eutectic solvents (DESs) of choline chloride and ethylene glycol (ChCl-Eth) showed the highest extraction efficiency of rutin from S. japonica. • Under optimal conditions, the extraction yield of ChCl-Eth was 1.34 times higher than that of methanol as solvent. • Rutin was recovered from the DES extracts using water as the antisolvent with a high recovery yield, and the DESs of ChCl-Eth could be productively recovered and reused at least 3 times. Elsevier 2023-11-08 /pmc/articles/PMC10679937/ /pubmed/38023307 http://dx.doi.org/10.1016/j.mex.2023.102479 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Chemical Engineering
Le, Nhan Trong
Nguyen, Trieu Phat Dac
Ho, Duc Viet
Phung, Huong Thanh
Nguyen, Hoai Thi
A green method to extract rutin from Sophora japonica L.
title A green method to extract rutin from Sophora japonica L.
title_full A green method to extract rutin from Sophora japonica L.
title_fullStr A green method to extract rutin from Sophora japonica L.
title_full_unstemmed A green method to extract rutin from Sophora japonica L.
title_short A green method to extract rutin from Sophora japonica L.
title_sort green method to extract rutin from sophora japonica l.
topic Chemical Engineering
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679937/
https://www.ncbi.nlm.nih.gov/pubmed/38023307
http://dx.doi.org/10.1016/j.mex.2023.102479
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