A C1qTNF3 collagen domain fusion chaperones diverse secreted proteins and anti-Aβ scFvs: Applications for gene therapies

Enhancing production of protein cargoes delivered by gene therapies can improve efficacy by reducing the amount of vector or simply increasing transgene expression levels. We explored the utility of a 126-amino acid collagen domain (CD) derived from the C1qTNF3 protein as a fusion partner to chapero...

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Detalles Bibliográficos
Autores principales: Moore, Brenda D., Ran, Yong, Goodwin, Marshall S., Komatineni, Kavitha, McFarland, Karen N., Dillon, Kristy, Charles, Caleb, Ryu, Danny, Liu, Xuefei, Prokop, Stefan, Giasson, Benoit I., Golde, Todd E., Levites, Yona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679951/
https://www.ncbi.nlm.nih.gov/pubmed/38027063
http://dx.doi.org/10.1016/j.omtm.2023.101146

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