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A bronchial gene signature specific for severe COPD that is retained in the nose

INTRODUCTION: A subset of COPD patients develops advanced disease with severe airflow obstruction, hyperinflation and extensive emphysema. We propose that the pathogenesis in these patients differs from mild–moderate COPD and is reflected by bronchial gene expression. The aim of the present study wa...

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Detalles Bibliográficos
Autores principales: van Nijnatten, Jos, Faiz, Alen, Timens, Wim, Guryev, Victor, Slebos, Dirk-Jan, Klooster, Karin, Hartman, Jorine E., Kole, Tessa, Choy, David F., Chakrabarti, Arindam, Grimbaldeston, Michele, Rosenberger, Carrie M., Kerstjens, Huib, Brandsma, Corry-Anke, van den Berge, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680034/
https://www.ncbi.nlm.nih.gov/pubmed/38020574
http://dx.doi.org/10.1183/23120541.00354-2023