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A bronchial gene signature specific for severe COPD that is retained in the nose
INTRODUCTION: A subset of COPD patients develops advanced disease with severe airflow obstruction, hyperinflation and extensive emphysema. We propose that the pathogenesis in these patients differs from mild–moderate COPD and is reflected by bronchial gene expression. The aim of the present study wa...
Autores principales: | van Nijnatten, Jos, Faiz, Alen, Timens, Wim, Guryev, Victor, Slebos, Dirk-Jan, Klooster, Karin, Hartman, Jorine E., Kole, Tessa, Choy, David F., Chakrabarti, Arindam, Grimbaldeston, Michele, Rosenberger, Carrie M., Kerstjens, Huib, Brandsma, Corry-Anke, van den Berge, Maarten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680034/ https://www.ncbi.nlm.nih.gov/pubmed/38020574 http://dx.doi.org/10.1183/23120541.00354-2023 |
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