RSK3 switches cell fate: from stress-induced senescence to malignant progression

BACKGROUND: TGFβ induces several cell phenotypes including senescence, a stable cell cycle arrest accompanied by a secretory program, and epithelial-mesenchymal transition (EMT) in normal epithelial cells. During carcinogenesis cells lose the ability to undergo senescence in response to TGFβ but the...

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Detalles Bibliográficos
Autores principales: Huna, Anda, Flaman, Jean-Michel, Lodillinsky, Catalina, Zhu, Kexin, Makulyte, Gabriela, Pakulska, Victoria, Coute, Yohann, Ruisseaux, Clémence, Saintigny, Pierre, Hernandez-Vargas, Hector, Defossez, Pierre-Antoine, Boissan, Mathieu, Martin, Nadine, Bernard, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680185/
https://www.ncbi.nlm.nih.gov/pubmed/38008756
http://dx.doi.org/10.1186/s13046-023-02909-5

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