Hypothermia combined with extracellular vesicles from clonally expanded immortalized mesenchymal stromal cells improves neurodevelopmental impairment in neonatal hypoxic-ischemic brain injury

BACKGROUND: Neonatal encephalopathy following hypoxia–ischemia (HI) is a leading cause of childhood death and morbidity. Hypothermia (HT), the only available but obligatory therapy is limited due to a short therapeutic window and limited efficacy. An adjuvant therapy overcoming limitations of HT is...

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Detalles Bibliográficos
Autores principales: Labusek, Nicole, Ghari, Parnian, Mouloud, Yanis, Köster, Christian, Diesterbeck, Eva, Hadamitzky, Martin, Felderhoff-Müser, Ursula, Bendix, Ivo, Giebel, Bernd, Herz, Josephine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680187/
https://www.ncbi.nlm.nih.gov/pubmed/38012640
http://dx.doi.org/10.1186/s12974-023-02961-0

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