OTUD1 ameliorates cerebral ischemic injury through inhibiting inflammation by disrupting K63-linked deubiquitination of RIP2

BACKGROUND: Inflammatory response triggered by innate immunity plays a pivotal element in the progress of ischemic stroke. Receptor-interacting kinase 2 (RIP2) is implicated in maintaining immunity homeostasis and regulating inflammatory response. However, the underlying mechanism of RIP2 in ischemi...

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Detalles Bibliográficos
Autores principales: Zheng, Shengnan, Li, Yiquan, Song, Xiaomeng, Wu, Mengting, Yu, Lu, Huang, Gan, Liu, Tengfei, Zhang, Lei, Shang, Mingmei, Zhu, Qingfen, Gao, Chengjiang, Chen, Lin, Liu, Huiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680203/
https://www.ncbi.nlm.nih.gov/pubmed/38012669
http://dx.doi.org/10.1186/s12974-023-02968-7

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