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SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression

The cGAS/STING cytosolic DNA-sensing pathway plays a significant role in antitumor immunity. Expression of STING is tightly regulated and commonly reduced or defective in many types of cancer. We have identified SIX4 as a significant regulator of STING expression in colon cancer cells. We showed tha...

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Detalles Bibliográficos
Autores principales:	Liang, Beiyuan, Zhang, Evan H., Ye, Zhen, Storts, Hayden, Jin, Wei, Zheng, Xinru, Hylton, Hannah, Zaleski, Olivia, Xing, Xuanxuan, Miles, Wayne, Wang, Jing J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680432/ https://www.ncbi.nlm.nih.gov/pubmed/37888903 http://dx.doi.org/10.1158/2767-9764.CRC-23-0265

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