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Blocking CD40 Alleviates Th1 and Th17 Cell Responses in Elastin Peptide-Induced Murine Emphysema

PURPOSE: To investigate the role of the CD40-CD40 ligand (CD40L) pathway in the regulation of Th1, Th17, and regulatory T (Treg)-cell responses in an elastin peptide (EP)-induced autoimmune emphysema mouse model. METHODS: BALB/c mice were transnasally treated with EP on day 0, injected intravenously...

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Detalles Bibliográficos
Autores principales: Ma, Tingting, Zhang, Hui, Weng, Yuqing, Tang, Shudan, Mao, Jinshan, Feng, Xin, Zhang, Yuxin, Zhang, Jianquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680472/
https://www.ncbi.nlm.nih.gov/pubmed/38022831
http://dx.doi.org/10.2147/COPD.S428832

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