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Хирургическое лечение феохромоцитом

This review article contains a summary of modern aspects of preoperative preparation, surgical treatment, and follow-up of patients with adrenal pheochromocytomas. The main component of preoperative preparation is the use of alpha-blockers. The need to prescribe them to all patients is increasingly...

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Autores principales: Шихмагомедов, Ш. Ш., Реброва, Д. В., Краснов, Л. М., Фёдоров, Е. А., Чинчук, И. К., Черников, Р. А., Русаков, В. Ф., Слепцов, И. В., Згода, Е. А.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrinology Research Centre 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680547/
https://www.ncbi.nlm.nih.gov/pubmed/37968950
http://dx.doi.org/10.14341/probl13283
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author Шихмагомедов, Ш. Ш.
Реброва, Д. В.
Краснов, Л. М.
Фёдоров, Е. А.
Чинчук, И. К.
Черников, Р. А.
Русаков, В. Ф.
Слепцов, И. В.
Згода, Е. А.
author_facet Шихмагомедов, Ш. Ш.
Реброва, Д. В.
Краснов, Л. М.
Фёдоров, Е. А.
Чинчук, И. К.
Черников, Р. А.
Русаков, В. Ф.
Слепцов, И. В.
Згода, Е. А.
author_sort Шихмагомедов, Ш. Ш.
collection PubMed
description This review article contains a summary of modern aspects of preoperative preparation, surgical treatment, and follow-up of patients with adrenal pheochromocytomas. The main component of preoperative preparation is the use of alpha-blockers. The need to prescribe them to all patients is increasingly disputed, especially for patients without severe hypertension. An increasing number of publications demonstrate positive results of treatment without the use of alpha-blockers, advocating an individual approach and the use of the drug according to certain indications. Minimally invasive endoscopic techniques of adrenalectomy have become widespread in surgical treatment. They are represented by laparoscopic and retroperitonescopic technic, including using their single-port modifications. The earliest possible intersection of the central vein in the past was considered the most important aspect of adrenalectomy for pheochromocytoma, currently, due to the development of surgical techniques and anesthesiological manuals, this has ceased to be a mandatory rule of successful surgery. Despite the significant influence of the intersection of this vessel on intraoperative hemodynamics, surgical tactics with its later intersection have their own justifications and do not lead to a deterioration in treatment results. The standard volume of surgical intervention for pheochromocytomas is total adrenalectomy, however, in the presence of hereditary syndromes, such as multiple endocrine neoplasia type 2 syndrome, neurofibomatosis type 1, von Hippel-Lindau syndrome, it is possible to perform cortical-sparing adrenalectomy.
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spelling pubmed-106805472023-11-11 Хирургическое лечение феохромоцитом Шихмагомедов, Ш. Ш. Реброва, Д. В. Краснов, Л. М. Фёдоров, Е. А. Чинчук, И. К. Черников, Р. А. Русаков, В. Ф. Слепцов, И. В. Згода, Е. А. Probl Endokrinol (Mosk) Research Article This review article contains a summary of modern aspects of preoperative preparation, surgical treatment, and follow-up of patients with adrenal pheochromocytomas. The main component of preoperative preparation is the use of alpha-blockers. The need to prescribe them to all patients is increasingly disputed, especially for patients without severe hypertension. An increasing number of publications demonstrate positive results of treatment without the use of alpha-blockers, advocating an individual approach and the use of the drug according to certain indications. Minimally invasive endoscopic techniques of adrenalectomy have become widespread in surgical treatment. They are represented by laparoscopic and retroperitonescopic technic, including using their single-port modifications. The earliest possible intersection of the central vein in the past was considered the most important aspect of adrenalectomy for pheochromocytoma, currently, due to the development of surgical techniques and anesthesiological manuals, this has ceased to be a mandatory rule of successful surgery. Despite the significant influence of the intersection of this vessel on intraoperative hemodynamics, surgical tactics with its later intersection have their own justifications and do not lead to a deterioration in treatment results. The standard volume of surgical intervention for pheochromocytomas is total adrenalectomy, however, in the presence of hereditary syndromes, such as multiple endocrine neoplasia type 2 syndrome, neurofibomatosis type 1, von Hippel-Lindau syndrome, it is possible to perform cortical-sparing adrenalectomy. Endocrinology Research Centre 2023-11-11 /pmc/articles/PMC10680547/ /pubmed/37968950 http://dx.doi.org/10.14341/probl13283 Text en Copyright © Endocrinology Research Centre, 2023 https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 License.
spellingShingle Research Article
Шихмагомедов, Ш. Ш.
Реброва, Д. В.
Краснов, Л. М.
Фёдоров, Е. А.
Чинчук, И. К.
Черников, Р. А.
Русаков, В. Ф.
Слепцов, И. В.
Згода, Е. А.
Хирургическое лечение феохромоцитом
title Хирургическое лечение феохромоцитом
title_full Хирургическое лечение феохромоцитом
title_fullStr Хирургическое лечение феохромоцитом
title_full_unstemmed Хирургическое лечение феохромоцитом
title_short Хирургическое лечение феохромоцитом
title_sort хирургическое лечение феохромоцитом
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680547/
https://www.ncbi.nlm.nih.gov/pubmed/37968950
http://dx.doi.org/10.14341/probl13283
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