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Thyroid hormone increases fatty acid use in fetal ovine cardiac myocytes

Cardiac metabolic substrate preference shifts at parturition from carbohydrates to fatty acids. We hypothesized that thyroid hormone (T(3)) and palmitic acid (PA) stimulate fetal cardiomyocyte oxidative metabolism capacity. T(3) was infused into fetal sheep to a target of 1.5 nM. Dispersed cardiomyo...

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Detalles Bibliográficos
Autores principales: Chattergoon, Natasha, Louey, Samantha, Jonker, Sonnet S., Thornburg, Kent L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680578/
https://www.ncbi.nlm.nih.gov/pubmed/38010207
http://dx.doi.org/10.14814/phy2.15865