Engineered odorant receptors illuminate structural principles of odor discrimination

A central challenge in olfaction is understanding how the olfactory system detects and distinguishes odorants with diverse physicochemical properties and molecular configurations. Vertebrate animals perceive odors via G protein-coupled odorant receptors (ORs). In humans, ~400 ORs enable the sense of...

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Detalles Bibliográficos
Autores principales: de March, Claire A., Ma, Ning, Billesbølle, Christian B., Tewari, Jeevan, del Torrent, Claudia Llinas, van der Velden, Wijnand J. C., Ojiro, Ichie, Takayama, Ikumi, Faust, Bryan, Li, Linus, Vaidehi, Nagarajan, Manglik, Aashish, Matsunami, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680712/
https://www.ncbi.nlm.nih.gov/pubmed/38014344
http://dx.doi.org/10.1101/2023.11.16.567230

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