Deep learning and direct sequencing of labeled RNA captures transcriptome dynamics

Quantification of the dynamics of RNA metabolism is essential for understanding gene regulation in health and disease. Existing methods rely on metabolic labeling of nascent RNAs and physical separation or inference of labeling through PCR-generated mutations, followed by short-read sequencing. Howe...

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Detalles Bibliográficos
Autores principales: Martinek, Vlastimil, Martin, Jessica, Belair, Cedric, Payea, Matthew J, Malla, Sulochan, Alexiou, Panagiotis, Maragkakis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680836/
https://www.ncbi.nlm.nih.gov/pubmed/38014155
http://dx.doi.org/10.1101/2023.11.17.567581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680836/
https://www.ncbi.nlm.nih.gov/pubmed/38014155
http://dx.doi.org/10.1101/2023.11.17.567581

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