Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway

Age is a prominent risk factor for cardiometabolic disease, and often leads to heart structural and functional changes. However, precise molecular mechanisms underlying cardiac remodeling and dysfunction resulting from physiological aging per se remain elusive. Understanding these mechanisms require...

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Detalles Bibliográficos
Autores principales: Grilo, Luís F., Zimmerman, Kip D., Puppala, Sobha, Chan, Jeannie, Huber, Hillary F., Li, Ge, Jadhav, Avinash Y. L., Wang, Benlian, Li, Cun, Clarke, Geoffrey D., Register, Thomas C., Oliveira, Paulo J., Nathanielsz, Peter W., Olivier, Michael, Pereira, Susana P., Cox, Laura A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680868/
https://www.ncbi.nlm.nih.gov/pubmed/38014295
http://dx.doi.org/10.1101/2023.11.17.567640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680868/
https://www.ncbi.nlm.nih.gov/pubmed/38014295
http://dx.doi.org/10.1101/2023.11.17.567640

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